Netherlands Amsterdam

AmsterdamUMC, location AMC (Respiratory Medicine)

Department of Respiratory Medicine

Brief Overview

The Department of Respiratory Medicine of the Academic Medical Center, University of Amsterdam, covers the full spectrum of academic activities in the area of respiratory health and disease. This includes: Clinical Care, Research, Teaching and training.

The mission of the department is:

1. To prevend and combat lung diseases at the highest standard of medical care

2. To develop and implement innovative diagnostic and therapeutic procedures

3. To produce integrative medical research driven by both clinical and basic researchers

4. To teach and educate under- and postgraduate students towards MD and PhD degrees

5. To train medical specialists (pulmonologists) based on national and Hermes standards

Research Areas

Asthma\Biomarkers\Cystic fibrosis\Genetics\Paediatrics

Host center eligibility

Global fellowships (return phase only)\ European fellowships

Research infrastructure/facilities

1. Clinical facilities (outpatient clinic, hospital ward, Medium Care, Intensive Care, imaging, pathology, bacterology, virology, routine labs)

2. Animal Research (Murine models of allergy and airway inflammation, Transgenic and knock-out animals, whole body box and Flexivent for lung function)

3. Experimental Immunology and microbiology (Luminex, ELISA’s, Elispot, flow cytometry, state of the art molecular biology, state of the art immuno-histochemistry, cell culturing (primary bronchial epithelial cells)

4. Clinical Research Unit (Prospective clinical cohorts of severe asthma, adult onset asthma, COPD, and wheezy infants, Experimental human in vivo rhinovirus inoculation in asthma and COPD, inhaled allergen challenge, metacholine and other challenges, sputum induction.

Research funding/Resources

1. Clinical facilities (outpatient clinic, hospital ward, Medium & Intensive Care, imaging, pathology)

2. Animal Research (Murine models of allergy and airway inflammation, Transgenic and knock-out animals)

3. Experimental Immunology and microbiology (Luminex, ELISA’s, flow cytometry, biology, immuno-histochemistry, cell culturing)

4. Clinical Research Unit

5. Bronchial Endoscopy (bronchoscopy, endobronchial biopsies, broncoalveolar lavage, transbronchial needle aspiration, endosonography, transthoracic ultrasound, thoracoscopy, fluoroscopy)

6. Adult and Pediatric lung function

7. Breathomics (Tailored sampling devices for exhaled air in adults, children and infants, composite nano-sensor arrays platform for eNose assessments, GC-MS).

8. Transcriptomics and microbiome analysis (Next generation sequencing, multiplex rt-PCR for respiratory viruses

Links to non-academic sector

Several public-private partnership projects

Experience hosting international researchers, career development & training programmes, outreach activities

We have hosted more than 5 international post-docs within our department. The AMC Graduate School organises 32 courses for PhD’s and Post-docs. This includes:

1. General skills (e.g. lab safety, career development, project management)

2. Scientific methods (e.g. biostatistics, epidemiology, -omics methods)

3. Specific areas (e.g. infectious diseases, gene targeting, advanced immunology etc)

The course take 2-10 days and are running 2-6 times per year.

The AMC Graduate school organized courses specifically focused on post-docs in: Scientific project management, Scientific career development (this includes intensive coaching), Entrepeneurship.

The fellowship recipients have an access to these courses that are part of the Graduate School. However, they need to go on a waiting list. The time that a person has to wait depends on the course. For some there is a direct access, whilst others might have to wait for a while.

HR Excellence in Research – EU award