Metabolomics has emerged as a powerful tool in understanding complex biological systems. These techniques shed light on the molecular mechanisms underlying disease pathogenesis and progression, especially but not exclusively when cellular metabolism is dysregulated. Moreover, metabolic signatures or components thereof can be used as disease biomarkers. It can be applied on a variety of samples, including bronchoalveolar lavage, plasma and urine.
- To understand the principles underlying metabolomic analyses (what is analysed and how, what type of information is yielded)
- To understand what sample types can be used for metabolomic analyses, how samples should be collected and stored, and which controls should be included
- To receive insight into how analyses are performed, how to make sense of the data obtained, how to connect readouts to biological processes
- Examples will be provided based on key publications using metabolomics to illustrate what type of questions can be addressed using this technology and how to critically review the technique in a paper
- Aspects of data sharing will be addressed
- Metabolomics basic principles
- How to connect metabolomics data to cellular processes
- How metabolomics can help understand pathogenic processes in lung diseases
- How metabolomics signatures can be used as disease biomarkers
- Basic Translational scientists
This webinar will include a workshop with interactive quizzes, Q&A with audience, presentation of seminal papers and introduction to analysis workflows.
After following this webinar, participants should be able to:
- Understand the relevance of metabolomics in disease characterization.
- Learn which steps are required to undertake and assess metabolomics.
An application for accreditation of this webinar has been made to the European Board for Accreditation in Pneumology (EBAP) for 1 CME credit per 1-hour attendance. If accredited, the CME credit will be granted upon attendance of at least 60 minutes during the live webinar only.
What is a webinar?
A webinar closely simulates a lecture-based teaching experience. The speaker can interact with the audience, just as in a classroom setting. During the webinar, you will be asked to share your opinion on issues related to the topic using interactive polls.
All participants will be able to hear the lecturer and see the slides throughout the presentation. As a participant you will be able to pose questions or discuss ideas with the other participants via the text chat facility and the speaker will respond to the questions via the microphone.
More information will be communicated in due course.
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- Airway diseases
- Interstitial lung diseases
- Paediatric respiratory diseases
- Pulmonary Vascular diseases
- Respiratory infections
- Thoracic oncology
- Basic Translational scientists