United Kingdom Southampton

National Institute for Health Research (NIHR) Southampton Biomedical Research Centre (BRC)

University of Southampton Faculty of Medicine, NIHR Southampton BRC Respiratory & Critical Care Theme

Brief Overview

The NIHR Southampton Biomedical Research Centre (BRC) brings together clinicians, scientists, methodologists, patients, trainees, facilities and equipment needed to study health, disease and treatments to advance respiratory health. The BRC is jointly led by the University of Southampton and University Hospital Southampton in facilities at the hospital, enabling some of the world’s leading experts to involve patients and the public in exploring new ways of tackling respiratory disease at every stage of life.

Research Areas

Asthma\COPD\Intensive care\Interstitial lung disease\Lung cancer

Host center eligibility

Global fellowships (return phase only)/European fellowships – in line with current status

Research infrastructure/facilities

The BRC provides endoscopy suites and clinic rooms, pressure-adapted laboratories to study infected patients, lung function and allergen challenge laboratories, and lipidomics /proteomics mass spectrometry suites in close proximity to our university laboratories thus integrating basic science with clinical research facilities. Basic science provision includes a comprehensive expertise spanning molecular biology and protein and lipid biochemistry, cellular immunology, cell and tissue culture. We also have expertise in murine models of infection, allergy and inflammation.
• Histochemistry Research Unit
• Biomedical Imaging Unit
• Clinical Trials Unit
• Body imaging & image analysis from HRCT, 3TMRI, SPECTCT

Research funding/Resources

Our core NIHR funding supports the infrastructure, established patient cohorts and small phase II POC studies enhanced by income from grants and commercial collaborations.  If any training needs identified are to be found in another NIHR centre then we can apply for an NIHR SPARC award to further facilitate this secondment.

Links to non-academic sector

The University of Southampton has its own Science Park which is home to successful science and technology business from start-ups through to industry-leading multinationals. Opportunities for learning also exist within the University.  The University of Southampton’s impressive spin-out record and success in commercialising academic research has been favourably compared with top US University, Stanford in a recent study compiled by the influential research firm, Library House. We are proud that five of the University’s 12 spin-out companies emerged from the Faculty of Medicine. Opportunities for secondment to the non-academic sector will be arranged depending on the training needs identified.

Experience hosting international researchers, career development & training programmes, outreach activities

Training of international postdoctoral researchers is a fundamental component of the BRC, with Education and Training in the Respiratory & Critical Care Theme being led by Dr Karl Staples. Training needs are assessed at induction by the supervisor with formal annual review and appraisal of career development.
Specialised scientific training is available in individual laboratories in accordance with the specific training needs of the trainee and the project. Formal training is well established through the University for a range of scientific techniques (e.g. flow cytometry, immunohistochemistry, electron microscopy, animal research) and transferrable skills such as presentation skills and outreach. Opportunities for outreach activities include LifeLab, the University Science & Engineering Day and attendance at the New Forest Show.
Development of specific clinical skills is accessed through the clinical skills department eg. lung function spirometry (accredited by the Association of Pulmonary Technicians/British Thoracic Society), skin prick testing and bronchial challenge.

HR Excellence in Research – EU award


Contact persons