Information provided by lung tissue analysis is crucial in a not negligible number of patients with a clinico-radiologic suspicion of Interstitial Lung Disease (ILD)
Informative data may be obtained by bronchoalveolar lavage (BAL) or regular transbronchial lung biopsy mainly in patients with acute/alveolar disorders (eosinophilic pneumonia, organizing pneumonia, diffuse alveolar damage due to different causes, alveolar proteinosis, infections) or in disorders that mainly affect the centrilobular zones (sarcoidosis, carcinomatous lymphangitis). In disorders having a more complex histopathologic background, liquid biopsy (BAL) or tiny lung samples are not sufficient. In the last scenario, surgical lung biopsy was considered the gold standard. However, this approach is feasible in patients < 65-70 years of age without significant comorbidities or functional lung impairment. The mortality due to this invasive approach is around 2% and significantly higher in the elderly, in those with significant lung impairment of with a clinical hypothesis of IPF or collagen-vascular disease. Transbronchial cryobiopsy is now a new endoscopic approach that allow to obtain larger lung tissue samples without crush artifacts. This approach appears to be a valid alternative to surgical lung biopsy. However specific guidelines assessing the clinical role of this approach were missing
This webinar will discuss the safety profile, the diagnostic yield, the prognostic impact, and the diagnostic accuracy of transbronchial cryiobiopsy in patients with ILD needing histopathologic confirmation for therapeutic decisions
- ILD or diffuse parenchymal lung disease.
- Surgical lung biopsy; transbronchial biopsy with flexible forceps; transbronchial cryobiopsy.
- The role of the multidisciplinary team in discussing information provided by transbronchial cryobiopsy.
- Needs for training in transbronchial cryobiopsy.
- Presentation and discussion of the recent ERS guidelines on transbronchial cryobiopsy in ILDs.
Discussion between clinicians with expertise in ILDs, transbronchial cryobiopsy and lung pathology.
Following this webinar, participants will be able to:
- Discuss the recommendations present in the ERS guidelines
- Identify the clinical role of transbronchial cryobiopsy in the context of MDD
- Review the steps that beginners needs to follow in order to implement transbronchial cryobiopsy in their own hospital or institute.
An application for accreditation of this webinar has been made to the European Board for Accreditation in Pneumology (EBAP) for 1 CME credit per 1-hour attendance. If accredited, the CME credit will be granted upon attendance of at least 60 minutes during the live webinar only.
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Diseases / methods
- Interstitial lung diseases
- Thoracic Surgeons