Netherlands Groningen

University Medical Center Groningen

Groningen Research Institute for Asthma and COPD (GRIAC)

Brief Overview

The Groningen Research Institute for Asthma and COPD (GRIAC) is dedicated to research on obstructive and pulmonary diseases on the edge of clinical and fundamental research. The main theme of GRIAC is unravelling the underlying mechanisms of the development, progression and remission of airway obstruction, allergy and airway hyperresponsiveness, their mutual interactions, and their relevance to treatment.

The multidisciplinary and translational research of GRIAC is the result of an intensive collaboration between the researchers of GRIAC, consisting of our members from different disciplines. The disciplines involved are allergology, experimental pulmonology and inflammation research, epidemiology, general practice, molecular pharmacology, pathology, paediatric pulmonology and allergology, pulmonology and respiratory insufficiency.

Research Areas

Asthma\COPD\Epidemiology\Epithelial cell\Genetics

Host center eligibility

Global fellowships (return phase only)\ European fellowships

Research infrastructure/facilities

GRIAC departments range from clinical (Pulmonology, Pediatrics) to more fundamental research (Epidemiology, Medical Biology and Pathology, Pharmacy, ERIBA).

We have organized our research in three  integrated subprograms on:

1. Epidemiology and genomics

2. Molecular Medicine: Pathophysiology and pathogenesis of chronic lung disease and drug target identification.

3.  Clinical Medicine: Assessment, modulation of and intervention in disease severity, progression and remission

We have state of the art resources to perform cutting edge, mulidisciplinary science, that includes access to and collection of primary patient material, genomic and proteomic technology, as well as cell cultures and animal models. Most recently, single

Research funding/Resources

We have several studies ongoing, that are a fundamental resource for our study, on asthma, severe COPD, but also on birth cohorts (LifeLines). Funding for our research comes from Lung Foundation of the Netherlands, Governmental bodies, as well as the European Union. We have many collaborations with industry.

Links to non-academic sector

GRIAC has two spin off companies, Aquilo ( and GPRI ( We have close collaborations with pharmaceutical industry, providing opportunities for networking and potentail secondments.

Experience hosting international researchers, career development & training programmes, outreach activities

We host international post docs from Australia, Asia, and South America, and the majority of PhD students have an international background. All GRIAC Meetings are held in English. Two RESPIRE postdocs that have completed their stay in Groningen now hold successfull faculty positions in other institutions. We have a strong link to patients, and 3 montly meetings with our patient advisory board. All GRIAC researchers can consult the board for input for their projects.

HR Excellence in Research – EU award