Spain Barcelona

Fundació Institut de Recerca de l’Hospital de la Santa Creu i Sant Pau

Respiratory Medicine Department

Brief overview

The Sant Pau Biomedical Research Institute (IIB Sant Pau) is one of the accredited, hospital-associated (Hospital de la Santa Creu i Sant Pau -HSCSP-, Universitat Autònoma de Barcelona) healthcare research institutes of the National Health System of Spain. Its mission is to promote basic, clinical, epidemiological, and health services research to contribute health improvements to the community. It aims at bridging basic/translational research with clinical practice so as to ultimately improve patient care. It is one of the most active research institutes in relation to translational research and the application of new discoveries to clinical practice in Spain.

Research areas

Asthma/Cell biology/Immunology/Molecular biology/Pharmacology

Host center eligibility

Global fellowships (return phase only)\European fellowships

Research infrastructure/facilities

The infrastructure comprises core facilities (animal facility, histopathology, cryopreservation, advanced microscopy, flow cytometry, genomics, proteomics); the Respiratory Medicine Department facility with its laboratory space equipped with a rodent mechanical ventilation and pulmonary function testing workstation, a certified class-II biocontainment facility for cell culture and viral gene transfer vector procedures (comprising a laminar flow hood, incubator, a cell culture centrifuge with active heating and biocontainment rotor capsules), ancillary laboratory support equipment, and office space; and a Medicines Research Center with an allocated facility for respiratory clinical trials (with a clinical research coordinator, research nurses, and equipped for complex trial protocols).

Research funding/resources

Respiratory research is funded through grants from Government agencies and scientific societies, participation in international programs, and clinical trials. Government funding comprises consecutive or overlapping operating grants from the Ministry of Science and Innovation programs. The leading international program is the ERS Severe Heterogeneous Asthma Research Collaboration, Patient-Centred (SHARP), which branches projects with industry sponsoring and an ongoing H2020 submission. The clinical trials are a significant funding source comprising Phase IIa to Phase IV studies for the pharma and biotech industry. We design and lead some of the trials. Industry investigator-driven grants contribute additionally.

Links to non-academic sector

Due to the translational research programme, the institute has had long lasting collaborations with SME´s and the pharmaceutical industry – cooperations The IIB Sant Pau manages the innovation and transfer development activity of 76 research groups. This portfolio includes 26 patent families (13 licensed), which have led to the creation of 6 active spin-offs.

The scientific activity is enhanced thanks to the collaboration with companies, universities, and other research institutes. In 2019, a total of 117 contracts were signed with industrial partners, around 20% of them with international ones.

Our institute is a member of several national and international platforms, associations, and clusters (EATRIS, among others), and holds links with Technological Centers that facilitate technological collaboration with industry.

Experience hosting international researchers, career development & training programmes, outreach activities

One of the foundational purposes of the IIB Sant Pau is to teach and train in the field of life and health sciences. The Institute is linked to the Universitat Autònoma de Barcelona (UAB), offers master’s, diploma, and doctoral programs, and promotes knowledge exchange among researchers and groups, as well as with the Sant Pau Hospital as the clinical counterpart. The research institute is located in the same physical area as the Sant Pau University Hospital and provides the basis for different training programs of the UAB. Currently, the IIB Sant Pau is the host institution for 89 foreign researchers. The Respiratory Department runs training programs in respiratory system immunobiology for foreign attendees and has experience in foreign postdoctoral fellow recruitment through advertising in Nature Jobs.

HR Excellence in Research – EU award