Journal article

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Aspirin Use and Respiratory Morbidity in COPD

Author(s): Fawzy A, Putcha N, Aaron CP et al

Chest 2019; 155: 519–527

Airway diseases

Digest Author(s): Sylianos Loukides, e-Learning Director / 8 March, 2019

Fawzy and co-authors, using the Spiromics cohort of COPD pateints, published an interesting propensity- score based study where the self-reported daily aspirin use resulted in lower rate of exacerbations, less symptoms and improved quality of life.


This observational study, with a retrospective approach, showed the beneficial effect of aspirin use in COPD but also raises the need for a future randomized trial. The main challenge is the biased effect of a possible cardiovascular disease.